Document Detail


Teflon granuloma in the nasopharynx: a potentially false-positive PET/CT finding.
MedLine Citation:
PMID:  15709148     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positron emission tomography (PET) has become a critical diagnostic tool in the discovery and staging of malignancies in the head and neck. Although PET is accurate for detecting cancer, increased 18 F-fluorodeoxyglucose (FDG) uptake can be seen in healthy tissues such as muscle, fat, and glands and uptake can be seen in tissues affected by inflammation or granulomatous disease. Combined PET and CT (PET/CT) can often overcome these difficulties by fusing anatomic and physiological data, but radiographic findings of some disease processes can be confusing even with fused imaging techniques. We present two cases of FDG uptake in the posterior pharynx, localized by combined PET/CT, which was initially interpreted as squamous cell carcinoma. The increased activity was ultimately attributed to Teflon-induced granulomas. It is important for radiologists to recognize potential causes of false-positive PET/CT findings to improve our diagnostic accuracy and to avoid unnecessary biopsies and surgeries.
Authors:
Chivonne Harrigal; Barton F Branstetter; Carl H Snyderman; Joseph Maroon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  26     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-14     Completed Date:  2005-12-22     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417-20     Citation Subset:  IM    
Affiliation:
Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15215, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Carcinoma, Squamous Cell / diagnosis*
False Positive Reactions
Granuloma, Foreign-Body / diagnosis*,  etiology*
Humans
Male
Nasopharyngeal Diseases / diagnosis*
Nasopharyngeal Neoplasms / diagnosis*
Polytetrafluoroethylene / adverse effects*
Positron-Emission Tomography*
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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