Document Detail

Technological development in mechanical ventilation.
MedLine Citation:
PMID:  19956072     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: Innovative modes of mechanical ventilation, mainly based on complex closed loop technologies, have been recently developed and are now available for clinical use. RECENT FINDINGS: Proportional assist ventilation with load-adjustable gain factors and neurally adjusted ventilatory assist are innovative modes of mechanical ventilation delivering a level of assistance proportional to the patient's effort, thus improving patient-ventilator synchrony and potentially representing a real clinical advantage. Adaptive support ventilation is a ventilatory mode delivering assisted (pressure support ventilation-like) or controlled breathing cycles (pressure-controlled-like), related to a minute ventilation target set by the clinician and on automated measurements of the patient's respiratory mechanics. Noisy pressure support ventilation, finally, is a recently described experimental evolution of pressure support, with some improvement potentials, but no clinical application till now. SUMMARY: The recently reported results with proportional assist ventilation with load-adjustable gain factors, neurally adjusted ventilatory assist, and adaptive support ventilation are, till now, mainly based on preliminary physiologic and clinical studies; although they seem to be promising, suggesting that closed loop-based modes could represent a real innovation in the field of mechanical ventilation, further clinical evaluation is needed before their widespread diffusion into clinical practice.
Giorgio Conti; Roberta Costa
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in critical care     Volume:  16     ISSN:  1531-7072     ISO Abbreviation:  Curr Opin Crit Care     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2009-12-29     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504454     Medline TA:  Curr Opin Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-33     Citation Subset:  IM    
Department of Intensive Care and Anesthesia, Catholic University of Rome, Rome, Italy.
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MeSH Terms
Diffusion of Innovation*
Respiration, Artificial / instrumentation*,  methods*
Respiratory Insufficiency / therapy
Therapy, Computer-Assisted

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