Document Detail

Techniques for the determination of left ventricular mass by signal-averaged electrocardiography.
MedLine Citation:
PMID:  2145736     Owner:  NLM     Status:  MEDLINE    
The standard ECG correlates poorly with LV mass. The SAECG precisely measures myocardial energy and may allow more exact noninvasive assessment of LV mass. A commercially available system (Corazonix Predictor I) was tested for its ability to reproduce and measure known input energy in square wave and QRS waveforms, using frequency bandwidths different from those used for late potential analysis. A test group of 15 patients was studied to determine optimum filter type and bandwidth for comparison of SAECG energy measurement versus LV mass as determined by echocardiography (Penn conversion) and LV hypertrophy via standard ECG criteria. The best means of energy measurement were maximum and total RMS voltage and the integral of the area under the QRS curve. Optimum correlation with echocardiography was seen with a bidirectional band-pass filter of 5 to 250 Hz applied either to the vector sum of the three orthogonal leads or to the Z lead alone (r values 0.61 to 0.73), which was equal to or superior to standard ECG LV hypertrophy determinants. A second group of 20 patients was studied prospectively to confirm these findings, which yielded similar results. Conclusion: (1) the SAECG when appropriately modified serves as a rapid noninvasive assessment of LV mass. (2) These modifications must examine the entire duration and energy spectrum of the surface ECG and not just the region of late potentials. (3) Very low frequencies (below 5 Hz) must be excluded to eliminate the energy present due to DC offset voltage.
J L Vacek; D B Wilson; G W Botteron; J Dobbins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  120     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-05     Completed Date:  1990-11-05     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  958-63     Citation Subset:  AIM; IM    
Section of Cardiovascular Diseases, University of Kansas Medical Center, MO.
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MeSH Terms
Cardiomegaly / diagnosis*
Electrocardiography / methods*
Heart / anatomy & histology*,  physiology
Heart Ventricles
Pilot Projects
Prospective Studies

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