Document Detail


Technical note: pig model for studying nutrient assimilation by the intestine and colon.
MedLine Citation:
PMID:  9263064     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have developed a system for chronically catheterizing 10- to 25-d-old pigs that permits stable isotope tracer studies of intestinal or colonic assimilation of nutrients. This model also can be used to ensure constant enteral feeding or to assess the rate of entry into the terminal ileum of carbohydrates, fats, and amino acids. A plastic cannula with a luminal flange can be surgically placed in the stomach for tracer studies of sugar digestion or for controlled infusion of any formula diet. A similar cannula can be placed in the cecum for infusion of tracer and(or) substrates for studies of fermentation. The cannula has been machined so that a washer and nut can be threaded onto it, allowing the entire apparatus to be fixed to the abdominal wall. The distal end protruding above the skin was tapered to fit standard i.v. extension tubing. A carotid arterial catheter was used to sample substrates for isotopic enrichment measurements.
Authors:
C L Kien; A H Ailabouni; R D Murray; P A Powers; R E McClead; J Kepner
Related Documents :
75834 - Adjuvant and immunostimulating activities (in the absence of freund's incomplete adjuva...
1227284 - Sulfuric acid effect on the deposition of radioactive aerosol in the respiratory tract ...
8117924 - The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (phip) b...
952894 - Comparative analysis of the nuclear basic proteins in rat, human, guinea pig, mouse and...
23042164 - Rare branched fatty acids characterize the lipid composition of the intra-aerobic metha...
17099274 - Measurements of binary diffusion coefficients, retention factors and partial molar volu...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of animal science     Volume:  75     ISSN:  0021-8812     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-27     Completed Date:  1997-10-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2161-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Ohio State University College of Medicine and Children's Hospital, Columbus 43205, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acids / metabolism,  pharmacokinetics*
Animals
Catheterization / methods,  veterinary*
Colon / metabolism*,  surgery
Diet / veterinary
Dietary Carbohydrates / metabolism*,  pharmacokinetics
Dietary Fats / metabolism,  pharmacokinetics*
Fermentation
Intestinal Absorption / physiology
Intestines / metabolism*,  surgery
Stomach / metabolism,  surgery
Swine / metabolism,  physiology*
Grant Support
ID/Acronym/Agency:
HD19773/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Dietary Carbohydrates; 0/Dietary Fats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Use of a raw meat-based diet or a dry kibble diet for sand cats (Felis margarita).
Next Document:  Growth and physiological responses to toxicosis in lines of mice selected for resistance or suscepti...