Document Detail


Technical achievement: transthoracic Doppler echocardiography can be used to detect LAD restenosis after coronary angioplasty.
MedLine Citation:
PMID:  11100389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the capability of transthoracic Doppler echocardiography (TTE) to detect and quantify the severity of restenosis in the left anterior descending coronary artery (LAD) after percutaneous transluminal coronary angioplasty (PTCA). We studied 10 consecutive patients assigned for quantitative coronary angiography (qCA) due to a recurrent angina pectoris after PTCA of the LAD. The LAD was visualized by TTE, and the presence of local turbulence and an increase in the blood flow velocity was regarded to indicate coronary stenosis. To assess the severity of the stenosis, the increase of blood flow velocity was measured. Angiography showed stenoses of various degrees (27-100%) in all patients. All stenoses were detectable using TTE. Moreover, the ratio of maximal blood flow velocity at the site of stenosis to the pre-stenotic blood flow velocity (M/P-ratio) correlated significantly with the reduction of the luminal diameter of LAD (r = 0.85, P < 0.003). A M/P-ratio higher than 3.0 predicted a diameter reduction of 50% or higher with sensitivity and specificity of 100% in patients with a subtotal stenosis (n = 9). Our results indicate that stenoses in the LAD could be found and the severity of the stenoses could be quantified reliably with TTE. This approach is totally non-invasive and less expensive than coronary angiography and can be used clinically in clarifying restenosis after coronary angioplasty.
Authors:
M Saraste; J W Koskenvuo; J Mikkola; L Pelttari; J O Toikka; J J Hartiala
Related Documents :
1546009 - Chronic stable angina pectoris. risk stratification and treatment.
1525809 - St segment alternans during coronary angioplasty.
9834859 - Optimal ("stent-like") acute angiographic results pursuable by traditional ptca.
11911909 - Mechanisms of ventricular fibrillation during coronary angioplasty: increased incidence...
8804779 - Ptca with the use of cardiac assist devices: risk stratification, short- and long-term ...
1615869 - Initial management and long-term clinical outcome of restenosis after initially success...
20642479 - Distribution and magnitude of shear stress after coronary bifurcation lesions stenting ...
15335309 - Gene delivery approaches to heart failure treatment.
6983409 - Risk factors and late recurrence of angina following myocardial revascularization.
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  20     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-02-09     Completed Date:  2001-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  428-33     Citation Subset:  IM    
Affiliation:
Department of Clinical Physiology, Turku University Central Hospital, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Transluminal, Percutaneous Coronary*
Blood Flow Velocity
Coronary Circulation*
Coronary Disease / therapy*,  ultrasonography*
Echocardiography, Doppler / methods*
Female
Humans
Male
Middle Aged
Postoperative Complications / ultrasonography
Recurrence
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Circadian systemic haemodynamics in borderline and mild hypertension.
Next Document:  Exhaled nitric oxide and its long-term variation in healthy non-smoking subjects.