Document Detail


Technetium-99m-pyrophosphate scintigraphy in patients with suspected acute myocardial infarction: impact of interobserver variability.
MedLine Citation:
PMID:  2992259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Technetium-99m-pyrophosphate (TcPYP) scintigraphy may have great value in patients with suspected acute myocardial infarction (AMI), but interobserver variability undoubtedly has adverse impact on predictive value. TcPYP scintigrams for 133 (80%) of 166 consecutive patients admitted for suspected AMI were interpreted independently by three experienced readers. Although there was complete agreement for 87 interpretations (65%), major discrepancies (i.e., at least one positive and one negative reading on the same scan) occurred for 28 scans (21%). To assess predictive accuracy, patients were categorized as follows: 36 had definite AMI manifest by new ECG Q waves and/or CK-MB evidence of AMI (group I), 56 were classified as possible AMI (group II), and 41 had AMI excluded (group III). Using only the definitive diagnostic categories (groups I and III), accuracy for each reader approximated 0.68, with no single reader being correct more often than any other.
Authors:
M L Fisher; M H Kelemen; D Collins; L Holder; G Winzelberg; G D Plotnick; F Morris; G W Moran; N H Carliner; R W Peters
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American heart journal     Volume:  110     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-09-09     Completed Date:  1985-09-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-52     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Creatine Kinase / blood
Diagnostic Errors
Diphosphates / diagnostic use*
Electrocardiography
Humans
Isoenzymes
Myocardial Infarction / diagnosis,  radionuclide imaging*
Prospective Studies
Technetium / diagnostic use*
Technetium Tc 99m Pyrophosphate
Chemical
Reg. No./Substance:
0/Diphosphates; 0/Isoenzymes; 0/Technetium Tc 99m Pyrophosphate; 7440-26-8/Technetium; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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