Document Detail

Technetium-99m HM-PAO single photon emission computed tomography imaging in transient global amnesia.
MedLine Citation:
PMID:  1580818     Owner:  NLM     Status:  MEDLINE    
Five right-handed patients with pure transient global amnesia were evaluated with technetium-99m hexamethylpropyleneamine oxime single photon emission computed tomography after the amnesic attack. Independent of the interval between the procedure and the amnesic episode, single photon emission computed tomography demonstrated a decreased cerebral blood flow in the left temporal lobe in one patient and in the left parietotemporal region in three patients, with a more marked reduction in the temporal lobe. The remaining three patients were normal. A control single photon emission computed tomographic study was carried out in one patient 3 months after the amnesic attack and showed a left-sided persistent temporal hypoperfusion. These findings suggest that in some patients, transient global amnesia can be due to a vascular mechanism requiring strong investigations for vascular risk factors and appropriate treatment. During a follow-up period of 12 to 32 months, none of the patients with regional hypoperfusion suffered cerebrovascular events, suggesting that single photon emission computed tomography has no predictive value for further stroke.
P Laloux; C Brichant; F Cauwe; P Decoster
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  49     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-06-09     Completed Date:  1992-06-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  543-6     Citation Subset:  AIM; IM    
Department of Neurology, Mont-Godinne Hospital, University of Louvain, Yvoir, Belgium.
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MeSH Terms
Amnesia / radionuclide imaging*
Brain / blood supply
Middle Aged
Organotechnetium Compounds / diagnostic use*
Oximes / diagnostic use*
Parietal Lobe / radionuclide imaging
Technetium Tc 99m Exametazime
Temporal Lobe / radionuclide imaging
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime

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