| Tear film evaporation--effect of age and gender. | |
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MedLine Citation:
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PMID: 20382067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Dry eye is more prevalent in older patients and among them more marked in women than men. The increase in dry eye with aging is traditionally thought to be associated with a decrease in tear production enhanced by hormonal changes. Clinical evidence of an abnormal lipid production system in older patients, in particular women is established. It is therefore postulated that the greater prevalence of dry eye problems in an older population has an evaporative component. METHODS: Tear film evaporation was measured with the Oregon Health Sciences University Evaporimeter at 30% and 40% humidity. RESULTS: 160 subjects less than 45 years old and 57 subjects aged 45 years or more formed the study population. The results revealed a significant effect of age (p < 0.001), gender (p < 0.001) and their interaction (p < 0.001): (i) the rate of evaporation was higher in the older age group at both humidities; (ii) the rate of evaporation was overall higher for women; and (iii) the synergic effect of age and gender was very marked: the rate of evaporation of older women was 34-80% higher than that of older men and 36-69% than younger women. CONCLUSIONS: Aging of the tear film includes a significant evaporative component characterised by higher tear film evaporation for the over 45 compared to younger people. Further, in the over 45 years of age, a significantly greater tear film evaporation was recorded in women than men. The findings have significant implications for the management of presbyopic dry eye sufferers. |
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Authors:
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Michel Guillon; Cécile Maïssa |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-04-09 |
Journal Detail:
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Title: Contact lens & anterior eye : the journal of the British Contact Lens Association Volume: 33 ISSN: 1476-5411 ISO Abbreviation: Cont Lens Anterior Eye Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-15 Completed Date: 2010-10-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712714 Medline TA: Cont Lens Anterior Eye Country: England |
Other Details:
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Languages: eng Pagination: 171-5 Citation Subset: IM |
Copyright Information:
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2010 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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OTG Research & Consultancy, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Aged, 80 and over Aging / metabolism* Disease Progression Dry Eye Syndromes / epidemiology, etiology*, metabolism England / epidemiology Female Follow-Up Studies Humans Humidity Incidence Male Middle Aged Prognosis Sex Factors Tears / metabolism* Time Factors Volatilization* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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