Document Detail


Teaching pulmonary gas exchange physiology using computer modeling.
MedLine Citation:
PMID:  18334570     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Students often have difficulty understanding the relationship of O(2) consumption, CO(2) production, cardiac output, and distribution of ventilation-perfusion ratios in the lung to the final arterial blood gas composition. To overcome this difficulty, I have developed an interactive computer simulation of pulmonary gas exchange that is web based and allows the student to vary multiple factors simultaneously and observe the final effect on the arterial blood gas composition (available at www.siumed.edu/medicine/pulm/vqmodeling.htm). In this article, the underlying mathematics of the computer model is presented, as is the teaching strategy. The simulation is applied to a typical clinical case drawn from the intensive care unit to demonstrate the interdependence of the above factors as well as the less-appreciated importance of the Bohr and Haldane effects in clinical pulmonary medicine. The use of a computer to vary the many interacting factors involved in the arterial blood gas composition appeals to today's students and demonstrates the importance of basic physiology to the actual practice of medicine.
Authors:
Kent S Kapitan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in physiology education     Volume:  32     ISSN:  1522-1229     ISO Abbreviation:  Adv Physiol Educ     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100913944     Medline TA:  Adv Physiol Educ     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  IM    
Affiliation:
Division of Pulmonary Medicine, School of Medicine, Southern Illinois University, Springfield, Illinois 62794-9636, USA. kkapitan@siumed.edu
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MeSH Terms
Descriptor/Qualifier:
Carbon Dioxide
Computer Simulation*
Curriculum
Educational Status
Humans
Models, Educational
Oxygen
Physiology / education*
Pulmonary Gas Exchange*
Teaching / methods*
Ventilation-Perfusion Ratio
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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