| Teaching Single-Cell Digital Analysis Using Droplet-Based Microfluidics. | |
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MedLine Citation:
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PMID: 22229495 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Microfluidics allows the manipulation of small quantities of reagents in a high-throughput manner and is therefore highly amenable to single cell characterization and more generally to digital analysis, with applications in fields as varied as genomics, diagnostics, directed evolution, and drug screening. The growing place of microfluidics in biology laboratories encouraged us to develop a teaching method where advanced undergraduate or first-year graduate-level students are taught to fabricate droplet-based microfluidic devices, characterize them, and finally use them to perform a digital analysis of bacterial samples based on a phenotypic marker. |
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Authors:
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Majdi Najah; Andrew D Griffiths; Michael Ryckelynck |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-9 |
Journal Detail:
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Title: Analytical chemistry Volume: - ISSN: 1520-6882 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370536 Medline TA: Anal Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institut de Science et d'Ingénierie Supramoléculaires (ISIS), Université de Strasbourg , CNRS UMR 7006, 8 allée Gaspard Monge, 67083 Strasbourg Cedex, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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