Document Detail

Teaching NeuroImages: Sciatic neuropathy after heroin abuse.
MedLine Citation:
PMID:  23960198     Owner:  NLM     Status:  In-Data-Review    
A 38-year-old woman presented with acute onset of severe pain in the left calf and foot after inhaling heroin. On examination, she had distal left lower extremity weakness and absent ankle jerk. EMG at 8 weeks suggested an axonal left sciatic neuropathy. HIV test was negative. Creatine kinase, erythrocyte sedimentation rate, and C-reactive protein were normal. MRI revealed prominent edema and enlargement of the left sciatic nerve without contrast enhancement (figure). She received weekly infusions of IV methylprednisolone leading to improvement in her symptoms and MRI findings. Recognized neuromuscular complications of acute heroin usage include mononeuropathy, polyradiculoplexopathy, and rhabdomyolysis secondary to possible inflammatory or toxic mechanisms.(1,2.)
Harvinder Kumar; Yuebing Li
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  81     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-08-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e51     Citation Subset:  AIM; IM    
From the Neuromuscular Center, Neurological Institute, Cleveland Clinic, OH.
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