| Tc-99m-MIBI-Negative Parathyroid Adenoma in Primary Hyperparathyroidism Detected by C-11-Methionine PET/CT After Previous Thyroid Surgery. | |
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MedLine Citation:
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PMID: 22064100 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 64-year-old woman with previous thyroid surgery developed symptomatic primary hyperparathyroidism, requiring hydration and furosemide. Cervical ultrasonography and an MRI of the neck were inconclusive. Early Tc-99m-methoxyisobutylisonitrile images 15 minutes post injection demonstrated focal uptake in the left lower thyroid lobe consistent with a small thyroid adenoma. Neither subtraction or late planar nor Tc-99m-methoxyisobutylisonitrile-SPECT images identified a focal area of increased uptake. PET/CT with 460 MBq C-11-methionine demonstrated a focal area of increased uptake in the right thyroid bed. Subsequent surgery confirmed a parathyroid adenoma of 1.4 cm in diameter. Histopathologic analysis showed a parathyroid adenoma of chief-cell type. |
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Authors:
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Matthias C Schmidt; Deniz Kahraman; Bernd Neumaier; Monika Ortmann; Dirk Stippel |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 36 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 1153-5 Citation Subset: IM |
Affiliation:
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From the *Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany; †Department of Cyclotron/Radiochemistry, Max Planck Institute for Neurological Research, Cologne, Germany; and ‡Institute of Pathology and §Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Cologne, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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