Document Detail

Tc-99m HMPAO-labeled WBC scans to detect appendicitis in women.
MedLine Citation:
PMID:  8896923     Owner:  NLM     Status:  MEDLINE    
Fifty female patients with acute abdomen and suspected appendicitis but atypical findings were included in this study. After intravenous injection of Tc-99m HMPAO-labeled WBCs, serial anterior abdominal/pelvic images at 30, 60, 120, and 240 minutes were obtained by a gamma camera. Any abnormal localization of WBC accumulation in the right lower quadrant of the abdomen with equal to or greater than bone marrow activity was considered as a positive scan. Thirty patients had positive WBC scans and underwent laparotomy, 28 had proven appendicitis, and 2 were not related to appendicitis. Twenty patients had negative WBC scans, 2 patients underwent laparotomy and were proved to have appendicitis. The remaining 18 patients did not undergo surgery and revealed no evidence of appendicitis after follow-up. The overall sensitivity, specificity, accuracy, and positive and negative predictive values for WBC scans to diagnose appendicitis is 93.3%, 90.0%, 92.0%, 93.3%, and 90.0%, respectively. In conclusion, Tc-99m HMPAO-labeled WBC imaging provides a rapid and highly accurate method for diagnosis of appendicitis in female patients with equivocal clinical examinations.
C H Kao; H T Lin; Y L Wang; S J Wang; T J Liu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  21     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-01-31     Completed Date:  1997-01-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  768-71     Citation Subset:  IM    
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China.
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MeSH Terms
Appendicitis / radionuclide imaging*
Child, Preschool
Cystitis / diagnosis
Diagnosis, Differential
Middle Aged
Organotechnetium Compounds / diagnostic use*
Oximes / diagnostic use*
Pelvic Inflammatory Disease / diagnosis
Sensitivity and Specificity
Technetium Tc 99m Exametazime
Reg. No./Substance:
0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime

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