| Taurine in cerebrospinal fluid in Friedreich's ataxia. | |
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MedLine Citation:
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PMID: 647488 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a previous study we reported low values of taurine and aspartic acid in the CSF of patients with Friedreich's ataxia, when the results were compared to the literature. Further studies have revealed that unforetold difficulties with the advertised methodology of sequential multi-sample amino acid analysis were responsible for low values in the determination of these two amino acids in the small volumes necessary for CSF. A corrected method is presented. With the latter method the differences disappear for CSF taurine and aspartic acid, but they remain valid for the previously reported blood and urine values in Friedreich's ataxia. GABA levels are also normal in Friedreich's ataxia CSF. |
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Authors:
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B Lemieux; R Giguere; A Barbeau; S Melancon; D Shapcott |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Volume: 5 ISSN: 0317-1671 ISO Abbreviation: Can J Neurol Sci Publication Date: 1978 Feb |
Date Detail:
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Created Date: 1978-07-24 Completed Date: 1978-07-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0415227 Medline TA: Can J Neurol Sci Country: CANADA |
Other Details:
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Languages: eng Pagination: 125-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Amino Acids / cerebrospinal fluid Aspartic Acid / cerebrospinal fluid Child Friedreich Ataxia / cerebrospinal fluid* Humans Male Taurine / cerebrospinal fluid* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 107-35-7/Taurine; 56-84-8/Aspartic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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