Document Detail

Taste perception with age: generic or specific losses in threshold sensitivity to the five basic tastes?
MedLine Citation:
PMID:  11555480     Owner:  NLM     Status:  MEDLINE    
Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests. A significant overall effect was found for age, but not for gender. However, an interaction effect of age and gender was found. The older men were less sensitive than the young men and women for acetic acid, sucrose, citric acid, sodium and potassium chloride and IMP. To detect the compound dissolved in water they needed a 1.32 (aspartame) to 5.70 times (IMP) higher concentration than the younger subjects. A significant decline in thresholds with replication was shown. The age effect found could be attributed predominantly to a generic taste loss.
J Mojet; E Christ-Hazelhof; J Heidema
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chemical senses     Volume:  26     ISSN:  0379-864X     ISO Abbreviation:  Chem. Senses     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-09-13     Completed Date:  2001-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8217190     Medline TA:  Chem Senses     Country:  England    
Other Details:
Languages:  eng     Pagination:  845-60     Citation Subset:  IM    
Unilever Research Vlaardingen, 3133 AT Vlaardingen.
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MeSH Terms
Acetic Acid / administration & dosage
Age Factors
Aging / physiology*
Citric Acid / administration & dosage
Food Preferences*
Inosine Monophosphate / administration & dosage
Potassium Chloride / administration & dosage
Sex Factors
Sodium Chloride / administration & dosage
Sucrose / administration & dosage
Taste Threshold*
Reg. No./Substance:
131-99-7/Inosine Monophosphate; 57-50-1/Sucrose; 64-19-7/Acetic Acid; 7447-40-7/Potassium Chloride; 7647-14-5/Sodium Chloride; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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