| Taste, olfactory and food texture reward processing in the brain and the control of appetite. | |
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MedLine Citation:
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PMID: 22989943 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Complementary neuronal recordings and functional neuroimaging in human subjects show that the primary taste cortex in the anterior insula provides separate and combined representations of the taste, temperature and texture (including fat texture) of food in the mouth independently of hunger and thus of reward value and pleasantness. One synapse on, in the orbitofrontal cortex (OFC), these sensory inputs are for some neurons combined by learning with olfactory and visual inputs, and these neurons encode food reward in that they only respond to food when hungry, and in that activations correlate with subjective pleasantness. Cognitive factors, including word-level descriptions, and attention modulate the representation of the reward value of food in the OFC and a region to which it projects, the anterior cingulate cortex. Further, there are individual differences in the representation of the reward value of food in the OFC. It is argued that over-eating and obesity are related in many cases to an increased reward value of the sensory inputs produced by foods, and their modulation by cognition and attention that over-ride existing satiety signals. It is proposed that control of all rather than one or several of these factors that influence food reward and eating may be important in the prevention and treatment of overeating and obesity. |
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Authors:
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Edmund T Rolls |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2012-09-19 |
Journal Detail:
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Title: The Proceedings of the Nutrition Society Volume: 71 ISSN: 1475-2719 ISO Abbreviation: Proc Nutr Soc Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-10-26 Completed Date: 2013-04-04 Revised Date: 2013-04-24 |
Medline Journal Info:
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Nlm Unique ID: 7505881 Medline TA: Proc Nutr Soc Country: England |
Other Details:
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Languages: eng Pagination: 488-501 Citation Subset: IM |
Affiliation:
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Department of Computer Science, Oxford Centre for Computational Neuroscience, Oxford CV4 7AL, UK. Edmund.Rolls@oxcns.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Appetite Regulation
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physiology* Attention Brain / physiology* Cognition Food Preferences / physiology*, psychology Humans Hunger / physiology Hyperphagia / physiopathology, psychology Learning* Obesity / physiopathology, psychology Reward* Satiation / physiology* Sensation / physiology* Smell / physiology Surface Properties Taste / physiology Temperature Vision, Ocular / physiology |
| Grant Support | |
ID/Acronym/Agency:
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//Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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