Document Detail


Taste, olfactory and food texture reward processing in the brain and the control of appetite.
MedLine Citation:
PMID:  22989943     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Complementary neuronal recordings and functional neuroimaging in human subjects show that the primary taste cortex in the anterior insula provides separate and combined representations of the taste, temperature and texture (including fat texture) of food in the mouth independently of hunger and thus of reward value and pleasantness. One synapse on, in the orbitofrontal cortex (OFC), these sensory inputs are for some neurons combined by learning with olfactory and visual inputs, and these neurons encode food reward in that they only respond to food when hungry, and in that activations correlate with subjective pleasantness. Cognitive factors, including word-level descriptions, and attention modulate the representation of the reward value of food in the OFC and a region to which it projects, the anterior cingulate cortex. Further, there are individual differences in the representation of the reward value of food in the OFC. It is argued that over-eating and obesity are related in many cases to an increased reward value of the sensory inputs produced by foods, and their modulation by cognition and attention that over-ride existing satiety signals. It is proposed that control of all rather than one or several of these factors that influence food reward and eating may be important in the prevention and treatment of overeating and obesity.
Authors:
Edmund T Rolls
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-09-19
Journal Detail:
Title:  The Proceedings of the Nutrition Society     Volume:  71     ISSN:  1475-2719     ISO Abbreviation:  Proc Nutr Soc     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-26     Completed Date:  2013-04-04     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  7505881     Medline TA:  Proc Nutr Soc     Country:  England    
Other Details:
Languages:  eng     Pagination:  488-501     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Appetite Regulation / physiology*
Attention
Brain / physiology*
Cognition
Food Preferences / physiology*,  psychology
Humans
Hunger / physiology
Hyperphagia / physiopathology,  psychology
Learning*
Obesity / physiopathology,  psychology
Reward*
Satiation / physiology*
Sensation / physiology*
Smell / physiology
Surface Properties
Taste / physiology
Temperature
Vision, Ocular / physiology
Grant Support
ID/Acronym/Agency:
//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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