Document Detail

Taste disorder involving Hunter's glossitis following total gastrectomy.
MedLine Citation:
PMID:  12132615     Owner:  NLM     Status:  MEDLINE    
We treated five patients with Hunter's glossitis following total gastrectomy. The major complaints of the patients were taste disorder and abnormal glossal sensation. In all five cases, the patient's tongue was red and smooth, and laboratory testing showed the presence of macrocytic anemia and decreased serum concentration of vitamin B12 (cyanocobalamin). Gustometry was carried out in four cases and the results documented the presence of taste disorder. All five patients were treated by administration of vitamin B12, which led to improvements in the appearance of the tongue, the patients' subjective complaints and the results of taste testing. When patients present with a red, smooth tongue, Hunter's glossitis (which can easily be improved by administration of vitamin B12) should be considered in the differential diagnosis.
Isamu Itoh; Akihiro Ikui; Minoru Ikeda; Hiroshi Tomita; Endo Souhei
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica. Supplementum     Volume:  -     ISSN:  0365-5237     ISO Abbreviation:  Acta Otolaryngol Suppl     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-22     Completed Date:  2003-01-24     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0370355     Medline TA:  Acta Otolaryngol Suppl     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  159-63     Citation Subset:  IM    
Department of Otorhinolaryngology, Nihon University School of Medicine, Tokyo, Japan.
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MeSH Terms
Glossitis / diagnosis,  etiology*
Middle Aged
Postoperative Complications*
Severity of Illness Index
Taste Disorders / diagnosis,  etiology*
Vitamin B 12 / therapeutic use
Reg. No./Substance:
68-19-9/Vitamin B 12

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