Document Detail


Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.
MedLine Citation:
PMID:  22272217     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have shown potential as multifunctional nanoparticles for clinical translation because they have been used asmagnetic resonance imaging (MRI) constrast agents in clinic and their features could be easily tailored by including targeting moieties, fluorescence dyes, or therapeutic agents. This review summarizes targeting strategies for construction of multifunctional nanoparticles including magnetic nanoparticles-based theranostic systems, and the various surface engineering strategies of nanoparticles for in vivo applications.
Authors:
Mi Kyung Yu; Jinho Park; Sangyong Jon
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Publication Detail:
Type:  Journal Article     Date:  2012-01-01
Journal Detail:
Title:  Theranostics     Volume:  2     ISSN:  1838-7640     ISO Abbreviation:  Theranostics     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101552395     Medline TA:  Theranostics     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  3-44     Citation Subset:  -    
Affiliation:
Cell Dynamics Research Center, School of Life Sciences, Gwangju Institute of Science and Technology, 261 Chemdangwagi-ro, Gwangju 500-712, Republic of Korea.
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