Document Detail


Targeting high-density lipoprotein cholesterol in the management of cardiovascular disease.
MedLine Citation:
PMID:  17982304     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association between low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol and the development of coronary heart disease (CHD) is well established. The management of CHD has traditionally focused on the reduction of LDL cholesterol or on the total lipid profile. Yet, treatment strategies for reducing risk in CHD also requires a focus on increasing low HDL cholesterol, as LDL cholesterol reduction alone is insufficient in preventing CHD events. This article reviews the strategies for targeting HDL cholesterol to optimize outcomes in CHD.
Authors:
Michael H Davidson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American heart hospital journal     Volume:  5     ISSN:  1541-9215     ISO Abbreviation:  Am Heart Hosp J     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-05     Completed Date:  2008-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156064     Medline TA:  Am Heart Hosp J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  210-6     Citation Subset:  IM    
Affiliation:
Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. michaeldavidson@radiantresearch.com
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MeSH Terms
Descriptor/Qualifier:
Antilipemic Agents / therapeutic use
Cardiovascular Diseases / drug therapy*
Cholesterol, HDL / drug effects*
Clofibric Acid / therapeutic use
Dyslipidemias / drug therapy*
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
Niacin / therapeutic use
Chemical
Reg. No./Substance:
0/Antilipemic Agents; 0/Cholesterol, HDL; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 59-67-6/Niacin; 882-09-7/Clofibric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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