Document Detail


Targeting hematoma expansion in ICH: Illusions of hope or hope to disillusion.
MedLine Citation:
PMID:  22744666     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Several variables are associated with poor outcome and mortality after intracerebral hemorrhage (ICH).(1) Among modifiable factors, hematoma expansion may have a predominant role, and has been the target of recent therapeutic trials in ICH. The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT) and Antihypertensive Treatment of Acute Cerebral Hemorrhage Study (ATACH-1) showed that intensive blood pressure (BP) lowering is associated with reduced hematoma expansion during the first 24 hours of ICH(2,3); the clinical effectiveness of this strategy is undergoing evaluation in phase III trials.
Authors:
Diogo C Haussen; Magdy Selim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-27
Journal Detail:
Title:  Neurology     Volume:  -     ISSN:  1526-632X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA.
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