Document Detail


Targeting Plk1 in cutaneous T-cell lymphomas (CTCLs).
MedLine Citation:
PMID:  21478668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Authors:
X Shawn Liu; Xiaoqi Liu
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Publication Detail:
Type:  Comment; News     Date:  2011-05-15
Journal Detail:
Title:  Cell cycle (Georgetown, Tex.)     Volume:  10     ISSN:  1551-4005     ISO Abbreviation:  Cell Cycle     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-24     Completed Date:  2011-09-28     Revised Date:  2011-11-02    
Medline Journal Info:
Nlm Unique ID:  101137841     Medline TA:  Cell Cycle     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1523     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Benzimidazoles / therapeutic use
Cell Cycle Proteins / antagonists & inhibitors*,  genetics,  metabolism
Cell Division
Cell Line, Tumor
Cyclin B1 / metabolism
G2 Phase
Humans
Lymphoma, T-Cell, Cutaneous / drug therapy*,  metabolism
Protein-Serine-Threonine Kinases / antagonists & inhibitors*,  genetics,  metabolism
Proto-Oncogene Proteins / antagonists & inhibitors*,  genetics,  metabolism
RNA Interference
RNA, Small Interfering / metabolism
Thiophenes / therapeutic use
cdc25 Phosphatases / metabolism
Chemical
Reg. No./Substance:
0/5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide; 0/Benzimidazoles; 0/Cell Cycle Proteins; 0/Cyclin B1; 0/Proto-Oncogene Proteins; 0/RNA, Small Interfering; 0/Thiophenes; EC 2.7.11.1/Protein-Serine-Threonine Kinases; EC 2.7.11.1/polo-like kinase 1; EC 3.1.3.48/CDC25C protein, human; EC 3.1.3.48/cdc25 Phosphatases
Comments/Corrections
Comment On:
Cell Cycle. 2011 Apr 15;10(8):1303-11   [PMID:  21436619 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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