Document Detail


Targeted thrombolysis strategies for neuroprotective effect.
MedLine Citation:
PMID:  25221585     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Stroke is usually treated by systemic thrombolytic therapy if the patient presents within an appropriate time window. There is also widespread interest in the development of thrombolytic agents that can be used in cases of delayed presentation. Current agents that can be used in cases of delayed presentation of nerve damage by thrombus. Current systemic thrombolytic therapy is associated with adverse effects such as fibrinogenolysis and bleeding. In an attempt to increase the efficacy, safety, and specificity of thrombolytic therapy, a number of targeted thrombolytic agents have been studied in recent years. This review focuses on the concepts underlying targeted thrombolytic therapy and describes recent drug developments in this field.
Authors:
Junping Zhang; Guoxing Ma; Zhimin Lv; Yu Zhou; Chunguang Wen; Yaqing Wu; Ruian Xu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neural regeneration research     Volume:  9     ISSN:  1673-5374     ISO Abbreviation:  Neural Regen Res     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-09-15     Completed Date:  2014-09-15     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  101316351     Medline TA:  Neural Regen Res     Country:  India    
Other Details:
Languages:  eng     Pagination:  1316-22     Citation Subset:  -    
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