Document Detail


Targeted delivery of vascular endothelial growth factor improves stem cell therapy in a rat myocardial infarction model.
MedLine Citation:
PMID:  24941463     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
FROM THE CLINICAL EDITOR: VEGF immunoliposomes targeting myocardial infarction tissue resulted in significantly higher attenuation of cardiac function loss when used in combination with mesenchymal stem cells. MSCs were previously found to have poor ability to restore cardiac tissue, likely as a result of poor blood supply in the affected areas. This new method counterbalances that weakness by the known effects of VEGF, as demonstrated in a rat model.
Authors:
Yuan Tang; Xiaoliang Gan; Rabe'e Cheheltani; Elizabeth Curran; Giuseppina Lamberti; Barbara Krynska; Mohammad F Kiani; Bin Wang
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Publication Detail:
Type:  Journal Article     Date:  2014-06-15
Journal Detail:
Title:  Nanomedicine : nanotechnology, biology, and medicine     Volume:  10     ISSN:  1549-9642     ISO Abbreviation:  Nanomedicine     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-12-02     Completed Date:  -     Revised Date:  2014-12-04    
Medline Journal Info:
Nlm Unique ID:  101233142     Medline TA:  Nanomedicine     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1711-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R21 HL109794/HL/NHLBI NIH HHS

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