| Target vessel reopening by guidewire insertion in ST-elevation myocardial infarction is a predictor of final TIMI flow and survival. | |
| | |
MedLine Citation:
|
PMID: 21103658 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
ST-elevation myocardial infarction (STEMI) results from acute thrombotic obstruction of a coronary artery. Percutaneous coronary intervention (PCI) is the treatment of choice to restore blood flow. The incidence of guidewire-induced reopening of the infarct-related coronary artery (IRA) and its association with post-procedural TIMI flow and long-term mortality were assessed. Angiograms of consecutive STEMI patients admitted to the catheter laboratory of the Medical University of Vienna between January 2003 and December 2005 were analysed. TIMI flow was graded prior to and after guidewire insertion into the distality of the IRA, and at the end of the procedure. Initial TIMI 0 flow was present in 476 (47.0%) of 1,012 cases. Target vessel reopening after guidewire insertion defined as any flow >TIMI 0 flow occurred in 150 patients (37.2%), and was associated with improved survival after a median of 914 (609-1,238) days (p=0.017). Reflow after guidewire insertion was an independent predictor of post-procedural TIMI flow (odds ratio=3.10, 95% confidence interval [CI]=1.64 - 5.86], p<0.001) and mortality (hazard ratio=0.51, CI=0.28 - 0.94], p=0.029). Target vessel reopening by guidewire insertion is a new predictor of prognosis. Target vessel flow after guidewire insertion should be assessed in a standardised fashion during PCI. |
| | |
Authors:
|
Christopher Adlbrecht; Klaus Distelmaier; Duygu Gündüz; Bassam Redwan; Christian Plass; Diana Bonderman; Alexandra Kaider; Günter Christ; Irene M Lang |
Related Documents
:
|
645928 - Effects of endurance exercise on coronary collateral blood flow in miniature swine. 18990338 - [effects of xuefu zhuyu oral liquid on hemorheology in patients with blood-stasis syndr... 8277078 - Improved doppler signal intensity in coronary arteries after intravenous peripheral inj... 7730678 - Computer simulation of the propagation of contrast medium in a coronary artery during o... 3572848 - Effect of amiloride on bulk flow and iontophoretic taste stimuli in the hamster. 3519568 - Pulmonary blood flow affects recovery from constriction in dog lung periphery. |
Publication Detail:
|
Type: Journal Article Date: 2010-11-23 |
Journal Detail:
|
Title: Thrombosis and haemostasis Volume: 105 ISSN: 0340-6245 ISO Abbreviation: Thromb. Haemost. Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2011-01-04 Completed Date: 2011-05-18 Revised Date: 2011-05-23 |
Medline Journal Info:
|
Nlm Unique ID: 7608063 Medline TA: Thromb Haemost Country: Germany |
Other Details:
|
Languages: eng Pagination: 52-8 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty / methods* Coronary Circulation Coronary Vessels / surgery* Female Humans Male Middle Aged Myocardial Infarction / mortality, therapy* Myocardial Revascularization Prognosis Regional Blood Flow Survival Rate Thrombolytic Therapy / methods* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Phase I study of Solulin, a novel recombinant soluble human thrombomodulin analogue.
Next Document: Thromboprophylaxis for recurrent miscarriage in women with or without thrombophilia. HABENOX: a rand...