Document Detail

Target localization for post-prostatectomy patients using CT and ultrasound image guidance.
MedLine Citation:
PMID:  16421499     Owner:  NLM     Status:  MEDLINE    
We conducted a study comparing B-mode acquisition and targeting (BAT) ultrasound alignments based on CT data in the postoperative setting. CT scans were obtained with a Primatom CT-on-rails on nine patients. Two CT scans were obtained each week, while setup error was minimized by BAT ultrasounds. For the first three patients, a direct comparison was performed. For the next six patients, a template based on the shifts from the week 1 CT during treatment was used for subsequent setup. Comparison of isocenter shifts between the BAT ultrasound and CT was made by the difference, absolute difference, and improvement (using CT alignments as the reference technique). A total of 90 image comparisons were made. The average interfraction motion was 3.2 mm in the lateral, 3.0 mm in the longitudinal, and 5.1 mm in the AP direction. The results suggest that the CTbased ultrasound templates can improve the localization of the prostate bed when the initial displacements are greater than 4 mm. For initial displacements smaller than 4 mm, the technique neither improved nor worsened target localization. However, ultrasound alignments performed without the use of a template deteriorated patient positioning for two out of three patients, demonstrating that the use of a CT template was beneficial even at small initial displacements.
Kamen Paskalev; Steven Feigenberg; Rojymon Jacob; Shawn McNeeley; Eric Horwitz; Robert Price; Charlie Ma; Alan Pollack
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2005-11-21
Journal Detail:
Title:  Journal of applied clinical medical physics / American College of Medical Physics     Volume:  6     ISSN:  1526-9914     ISO Abbreviation:  J Appl Clin Med Phys     Publication Date:  2005  
Date Detail:
Created Date:  2006-01-19     Completed Date:  2006-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101089176     Medline TA:  J Appl Clin Med Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  40-9     Citation Subset:  IM    
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
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MeSH Terms
Image Enhancement / methods
Image Interpretation, Computer-Assisted / methods
Neoplasm Recurrence, Local / diagnosis*,  radiotherapy*
Postoperative Care / methods
Prostatic Neoplasms / diagnosis*,  radiotherapy*,  surgery
Radiotherapy Planning, Computer-Assisted / methods
Radiotherapy, Computer-Assisted / methods*
Reproducibility of Results
Sensitivity and Specificity
Subtraction Technique
Surgery, Computer-Assisted / methods
Tomography, X-Ray Computed / methods*
Ultrasonography / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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