Document Detail


Tardive dyskinesia with Tourette-like syndrome.
MedLine Citation:
PMID:  6944306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a single case study of a 22 year old Japanese-Canadian woman who developed schizophrenia, was treated with ECT and several successive neuroleptics and subsequently, three years later, developed a tardive dyskinesia syndrome in association with a behavioral change resembling Gilles de la Tourette disease. This combined syndrome lasted seven months. After neuroleptics were withdrawn, the syndrome diminished in severity and disappeared after four months. Since both tardive dyskinesia and Tourette's disease are thought to be caused by relative overactivity or supersensitivity of the dopamine system, their reversible appearance after long term dopamine receptor blockade by neuroleptics can be expected in susceptible individuals.
Authors:
M V Seeman; J Patel; J Pyke
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  42     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1981-11-18     Completed Date:  1981-11-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  357-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Delayed-Action Preparations
Dyskinesia, Drug-Induced / complications*,  diagnosis
Female
Fluphenazine / adverse effects
Humans
Receptors, Dopamine / drug effects
Tourette Syndrome / chemically induced,  complications*,  psychology
Chemical
Reg. No./Substance:
0/Delayed-Action Preparations; 0/Receptors, Dopamine; 69-23-8/Fluphenazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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