Document Detail

Tap or bottled water consumption and spontaneous abortion: a 1986 case-control study in California.
MedLine Citation:
PMID:  1576215     Owner:  NLM     Status:  MEDLINE    
To investigate whether drinking tap or bottled water during pregnancy affects the risk of spontaneous abortion, we asked questions about water consumption in a large case-control study (626 cases, 1,300 controls). The study ascertained cases from hospital pathology laboratory reports of pregnancies that began in 1986 and obtained controls from birth certificates. The crude odds ratio for consumption of any vs no cold tapwater at home during the first trimester was 1.2 (95% confidence interval = 1.0-1.5), with no dose-response effect. The crude odds ratio for any bottled water consumption was 0.79 (95% confidence interval = 0.65-0.96), with a downward trend by amount consumed. Adjusting for many potential confounders did not alter these associations appreciably, although some variables appeared to be effect modifiers. The point estimates were stronger among women who were more difficult to contact, suggesting the possibility of bias.
G C Windham; S H Swan; L Fenster; R R Neutra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epidemiology (Cambridge, Mass.)     Volume:  3     ISSN:  1044-3983     ISO Abbreviation:  Epidemiology     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-06-10     Completed Date:  1992-06-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9009644     Medline TA:  Epidemiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
Environmental Health Investigations Branch, California Department of Health Services, Berkeley 94704.
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MeSH Terms
Abortion, Spontaneous / epidemiology*,  etiology,  pathology
Bias (Epidemiology)
California / epidemiology
Case-Control Studies
Effect Modifiers (Epidemiology)
Likelihood Functions
Logistic Models
Odds Ratio
Pathology Department, Hospital / statistics & numerical data
Residential Mobility
Water Supply / standards*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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