Document Detail


Tannin derived materials can block swarming motility and enhance biofilm formation in Pseudomonas aeruginosa.
MedLine Citation:
PMID:  23020753     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Surface-associated swarming motility is implicated in enhanced bacterial spreading and virulence, hence it follows that anti-swarming effectors could have clinical benefits. When investigating potential applications of anti-swarming materials it is important to consider whether the lack of swarming corresponds with an enhanced sessile biofilm lifestyle and resistance to antibiotics. In this study, well-defined tannins present in multiple plant materials (tannic acid (TA) and epigallocathecin gallate (EGCG)) and undefined cranberry powder (CP) were found to block swarming motility and enhance biofilm formation and resistance to tobramycin in Pseudomonas aeruginosa. In contrast, gallic acid (GA) did not completely block swarming motility and did not affect biofilm formation or tobramycin resistance. These data support the theory that nutritional conditions can elicit an inverse relationship between swarming motility and biofilm formation capacities. Although anti-swarmers exhibit the potential to yield clinical benefits, it is important to be aware of possible implications regarding biofilm formation and antibiotic resistance.
Authors:
Che O'May; Aliona Ciobanu; Howard Lam; Nathalie Tufenkji
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biofouling     Volume:  28     ISSN:  1029-2454     ISO Abbreviation:  Biofouling     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200331     Medline TA:  Biofouling     Country:  England    
Other Details:
Languages:  eng     Pagination:  1063-76     Citation Subset:  IM    
Affiliation:
a Department of Chemical Engineering , McGill University , Montreal , Canada.
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