| Tandemly arranged gene clusters of malarial parasites that are highly conserved and transcribed. | |
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MedLine Citation:
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PMID: 3033497 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A molecular clone containing a 5.8 kb Eco RI fragment was isolated from a genomic library of the rodent malarial parasite Plasmodium yoelii. The P. yoelii genome contains about 150 copies of this sequence, making up almost 3% of the DNA. These sequences are tandemly arrayed in head-to-tail configurations with the unit length of the repeat being 5.8 kb. Several poly(A+) RNAs of P. yoelii ranging from 1.6 to 0.3 kb are recognized by the 5.8 kb clone. Five additional species of malarial parasites (P. chabaudi, P. berghei, P. falciparum, P. knowlesi, and P. cynomolgi) contain tandemly repeated arrays of sequences having the same unit length of 5.8 kb, which readily hybridize to the sequence cloned from P. yoelii. |
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Authors:
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A B Vaidya; P Arasu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Molecular and biochemical parasitology Volume: 22 ISSN: 0166-6851 ISO Abbreviation: Mol. Biochem. Parasitol. Publication Date: 1987 Jan |
Date Detail:
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Created Date: 1987-05-26 Completed Date: 1987-05-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006324 Medline TA: Mol Biochem Parasitol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 249-57 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cloning, Molecular DNA / analysis*, genetics DNA Restriction Enzymes Deoxyribonuclease EcoRI Electrophoresis, Agar Gel Genes* Mice Nucleic Acid Hybridization Plasmodium / genetics* Plasmodium berghei / genetics Plasmodium falciparum / genetics Protein Biosynthesis Repetitive Sequences, Nucleic Acid Transcription, Genetic |
| Chemical | |
Reg. No./Substance:
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9007-49-2/DNA; EC 3.1.21.-/DNA Restriction Enzymes; EC 3.1.21.-/Deoxyribonuclease EcoRI |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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