Document Detail

Tandem Migration-Carboalkoxylation of o-Isocyanophenyl Acetals Leading to Benzoxazoles.
MedLine Citation:
PMID:  22251100     Owner:  NLM     Status:  Publisher    
An efficient approach to benzoxazoles via tandem migration-carboalkoxylation of o-isocyanophenyl acetals has been developed. Both a Lewis acid and base are essential for this reaction, and the BF(3)·OEt(2)/2,4,6-collidine combination is the best choice for cooperative transformation.
Takashi Okitsu; Kenta Nagase; Nobuhiko Nishio; Akimori Wada
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-17
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University, 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan.
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