| Tamoxifen enhances the control of acromegaly treated with somatostatin analog lanreotide. | |
MedLine Citation:
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PMID: 21221819 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We present the case of a 51-year old female patient with acromegaly that was resistant to somatostatin analogs and dopamine agonists. The patient was diagnosed with breast cancer requiring treatment with the anti-estrogen tamoxifen. Prior to initiating the treatment with tamoxifen, the IGF-I level was very high at 415% of the upper limit of normal for the patient's age and sex. During the tamoxifen treatment, the level of IGF-I dropped spectacularly down to normal levels. This observation highlights the effect of an anti-estrogen treatment in certain female patients with acromegaly. |
Authors:
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Jean-Christophe Maiza; Stéphane Castillo-Ros; Maria Matta; Antoine Bennet; Philippe Caron |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-8 |
Journal Detail:
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Title: Pituitary Volume: - ISSN: 1573-7403 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9814578 Medline TA: Pituitary Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Endocrinology and Metabolic Diseases, CHU Larrey, 24 Chemin de Pourvouville, TSA 30030, 31059, Toulouse Cedex 9, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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