Document Detail


Takotsubo syndrome and brachydactyly: a new heart-hand syndrome?
MedLine Citation:
PMID:  21448545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Takotsubo syndrome (TTS) is a transient myocardic hypoadyskinesis so called for its typically aspect like the cages used by Japanese fisherman to trap octopus. Presently, several etiologies were considered for the development of TTS, the most accredited ones suggest that stress, adrenoreceptor hyperactivity and estrogens are the most important causes of transient morphofunctional alterations of left ventricle. We describe the case of 60 year-old woman with a chest pain occurred after a quarrel. Because of this, she went to the Emergency Department (ED) where T wave flat in lead D-I, increase of CK-MB mass and Troponin I were found. Subsequently, a coronary-ventriculography was performed and a diagnosis of Takotsubo syndrome was made. Also a bilateral IV toe brachydactyly was noted. In medical literature, there are many syndromes described about the association between skeletal alteration of the hands and heart abnormalities (heart-hand syndrome). The Authors wonder if this case can belong to this kind of complex malformations as well as if a molecular-genetic trait can link the two clinical aspects.
Authors:
C Danese; S Bocchini; G Rubini; M Nardi; S Amato
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  La Clinica terapeutica     Volume:  162     ISSN:  1972-6007     ISO Abbreviation:  Clin Ter     Publication Date:  2011  
Date Detail:
Created Date:  2011-03-30     Completed Date:  2011-08-09     Revised Date:  2012-02-27    
Medline Journal Info:
Nlm Unique ID:  0372604     Medline TA:  Clin Ter     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Affiliation:
Department of Clinical Sciences, "Sapienza" University of Rome, Italy. chiara.danese@uniroma1.it
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / classification*
Chest Pain / etiology
Diagnosis, Differential
Electrocardiography
Female
Foot Deformities, Congenital / complications*
Heart Defects, Congenital
Humans
Middle Aged
Myocardial Infarction / diagnosis
Stress, Psychological / complications
Syndrome
Takotsubo Cardiomyopathy / blood,  complications*,  diagnosis,  ultrasonography
Toes / abnormalities*
Troponin I / blood
Chemical
Reg. No./Substance:
0/Troponin I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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