Document Detail

Takotsubo cardiomyopathy: reversible elevation in microcirculatory resistance.
MedLine Citation:
PMID:  21856251     Owner:  NLM     Status:  MEDLINE    
We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.
Jamie Layland; Robert Whitbourn; Andrew Macisaac; Jithendra Somaratne; Andrew Wilson
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiovascular revascularization medicine : including molecular interventions     Volume:  13     ISSN:  1878-0938     ISO Abbreviation:  Cardiovasc Revasc Med     Publication Date:    2012 Jan-Feb
Date Detail:
Created Date:  2012-01-23     Completed Date:  2012-10-29     Revised Date:  2013-03-04    
Medline Journal Info:
Nlm Unique ID:  101238551     Medline TA:  Cardiovasc Revasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  66-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Cardiology, St Vincent's Hospital, Melbourne, Victoria, Australia.
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MeSH Terms
Coronary Circulation / physiology*
Microcirculation / physiology*
Middle Aged
Takotsubo Cardiomyopathy / physiopathology*
Vascular Resistance*
Ventricular Function, Left / physiology*

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