Document Detail

Takotsubo cardiomyopathy induced by dobutamine infusion: a new phenomenon or an old disease with a new name.
MedLine Citation:
PMID:  20486954     Owner:  NLM     Status:  MEDLINE    
Takotsubo cardiomyopathy mimics acute myocardial infarction but is a separate clinical entity characterized by distinct wall motion abnormalities in the absence of obstructive coronary lesions. The prevalence of this condition is relatively uncommon yet has gained increasing recognition in recent years. It has rarely been associated with the use of dobutamine infusion during cardiac stress testing. We present in detail two cases of dobutamine-induced Takotsubo cardiomyopathy from our case series, one from 2002 and the other from 2008. While both cases display the typical features of Takotsubo cardiomyopathy, the former was initially diagnosed as dobutamine-induced vasospasm. These cases may provide insight into the pathophysiological mechanism of the condition and suggest that the increasing recognition of Takotsubo cardiomyopathy results from increasing familiarity of the condition.
William J Mosley; Amin Manuchehry; Colleen McEvoy; Vera Rigolin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  27     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-05-21     Completed Date:  2010-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E30-3     Citation Subset:  IM    
Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
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MeSH Terms
Cardiotonic Agents / pharmacology*
Diagnosis, Differential
Dobutamine / pharmacology*
Echocardiography, Stress
Heart / drug effects*
Inferior Wall Myocardial Infarction / diagnosis*,  physiopathology
Infusions, Intravenous
Middle Aged
Takotsubo Cardiomyopathy / chemically induced*,  diagnosis*,  physiopathology
Reg. No./Substance:
0/Cardiotonic Agents; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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