| Takayasu's arteritis. | |
| | |
MedLine Citation:
|
PMID: 7987037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Takayasu's arteritis is an uncommon condition with a unique constellation of clinical findings that continues to fascinate clinicians and researchers. Advances in the techniques used for classifying lymphocytes, recognizing markers of cellular activity, and detecting the presence of cytokines has produced more evidence that Takayasu's arteritis is a cell-mediated immune condition. The etiology(ies) or triggering mechanism(s) of the disease remains elusive. Alternatives to standard angiography for vascular imaging, such as digital subtraction angiography, duplex ultrasonography, and magnetic resonance imaging, have improved the facility with which the diagnosis and management of Takayasu's arteritis can be safely accomplished. Percutaneous transluminal angioplasty of the aorta and renal arteries is a safe and effective means to dilate symptomatic stenoses. In the short term, this technique provides relief from claudication, hypertension, and ischemia. Long-term follow-up suggests that restenosis at the angioplasty site occurs in a substantial number of patients. Whether this represents a fibrotic healing process or continued inflammation is unclear. Attempts to control the inflammation with anti-inflammatory and immunosuppressive agents continue to be reported. Prednisone plus methotrexate is a promising combination for use in this life-threatening condition of young people. |
| | |
Authors:
|
K M Pariser |
Related Documents
:
|
15048057 - Three-dimensional vascular angiography. 10696027 - Dynamic contrast-enhanced mr angiography and mr imaging of the carotid artery: high-res... 8230027 - Rheumatoid arthritis and vertebral artery occlusion: a case report with angiographic an... 19762707 - Noninvasive detection of vertebral artery stenosis: a comparison of contrast-enhanced m... 12879317 - Mri findings in acute idiopathic transverse myelopathy in children. 20089377 - Pet and pet/ct in endocrine tumours. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Current opinion in cardiology Volume: 9 ISSN: 0268-4705 ISO Abbreviation: Curr. Opin. Cardiol. Publication Date: 1994 Sep |
Date Detail:
|
Created Date: 1995-01-09 Completed Date: 1995-01-09 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8608087 Medline TA: Curr Opin Cardiol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 575-80 Citation Subset: IM |
Affiliation:
|
Division of Rheumatology, Faulkner Hospital, Jamaica Plain, MA 02130. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angioplasty, Balloon Autoimmune Diseases / diagnosis, immunology, therapy Diagnostic Imaging Humans Immunity, Cellular / immunology Immunosuppressive Agents / therapeutic use Takayasu Arteritis / diagnosis*, immunology, therapy |
| Chemical | |
Reg. No./Substance:
|
0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: What can we expect in antihypertensive drug therapy?
Next Document: Abdominal aortic aneurysms.