Document Detail


Takayasu's arteritis on steroid therapy. Seven years follow-up.
MedLine Citation:
PMID:  10705719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors report a 7 year follow-up of Takayasu's arteritis (TA) type III, group 1, in a young Italian woman. At diagnosis, at the age of 25, the echotomographic and angiographic studies showed narrow subclavian arteries, narrow abdominal aorta (diameter of 0.6-0.8 cm) below the renal arteries, stenotic left common carotid and renal arteries, and occluded upper mesenteric artery. With steroid therapy, (prednisone 50 mg/day per os), the erythrocyte sedimentation rate (ESR) normalized within 12 days. With a maintenance dosage of 7.5 mg/day per os, the patient achieved remission as documented by the absence of symptoms, the persistent normalization of ESR, and the improving of the diameter of the abdominal aorta (1.3-1.4 cm). On steroid therapy, the patient had a normal pregnancy and delivered a healthy baby girl. The disease has been stable for seven years. Recently, diabetes mellitus occurred and it has been treated with insulin therapy. The rising of ESR after tapering of steroid therapy (prednisone 5 mg per os on alternate days) suggests an alternative treatment with a cytotoxic agent.
Authors:
L Del Corso; D Moruzzo; M Agelli; F Pentimone
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Panminerva medica     Volume:  41     ISSN:  0031-0808     ISO Abbreviation:  Panminerva Med     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-04-11     Completed Date:  2000-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0421110     Medline TA:  Panminerva Med     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  355-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University of Pisa, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Inflammatory Agents / therapeutic use*
Diabetes Complications
Female
Humans
Infant, Newborn
Prednisone / therapeutic use*
Pregnancy
Pregnancy Complications / drug therapy
Takayasu Arteritis / complications,  drug therapy*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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