Document Detail

Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review.
MedLine Citation:
PMID:  23227437     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: Takayasu's arteritis (TA) is a rare and potentially devastating condition leading to prolonged morbidity and even death.
CASE DESCRIPTION: We report an 18-year-old female presenting with an acute ischemic stroke treated with intravenous thrombolysis and subsequent endovascular therapy (ET) with excellent results followed by chronic treatment with immunosuppressants after a formal diagnosis of TA. Following immunosupression, improvement was noted in critical stenoses of the extracranial large vessels.
CONCLUSION: These observations underscore the importance of early initiation of therapy to halt or even reverse vascular pathology, though frequent follow up is mandatory as relapse is common. In this article we provide brief review of the current literature on TA related to pathophysiology, criterion for diagnosis, therapy, and follow up.
Vishnumurthy Shushrutha Hedna; Akhil Patel; Sharathchandra Bidari; Melissa Elder; Brian L Hoh; Anthony Yachnis; Michael F Waters
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Publication Detail:
Type:  Journal Article     Date:  2012-10-27
Journal Detail:
Title:  Surgical neurology international     Volume:  3     ISSN:  2152-7806     ISO Abbreviation:  Surg Neurol Int     Publication Date:  2012  
Date Detail:
Created Date:  2012-12-11     Completed Date:  2012-12-12     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101535836     Medline TA:  Surg Neurol Int     Country:  India    
Other Details:
Languages:  eng     Pagination:  132     Citation Subset:  -    
Department of Neurology, University of Florida, Archer Road, Gainesville, Florida, 32611, USA.
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