Document Detail


Takayasu's arteritis associated with antiphospholipid antibodies. Report of two cases.
MedLine Citation:
PMID:  8638879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors describe 2 patients with Takayasu's arteritis in whom lupus anticoagulant was positive and the titer of anticardiolipin antibody was elevated. One patient developed diffusely stenotic and occlusive changes in the multiple larger arteries. Histology of the small-sized arteries in another patient showed occlusive vasculitis without thrombosis, in addition to the findings in large-sized arteries compatible with Takayasu's disease. These findings are uncommon in Takayasu's arteritis. These findings suggest that antiphospholipid antibodies may have contributed to the pathogenesis of the extensive vasculopathy and may have triggered vasculitis in these patients.
Authors:
K Yokoi; E Hosoi; M Akaike; T Shigekiyo; S Saito
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  47     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-07-05     Completed Date:  1996-07-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-9     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, School of Medicine, The University of Tokushima, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Antibodies, Antiphospholipid / analysis*
Arterial Occlusive Diseases / immunology,  pathology
Fatal Outcome
Female
Humans
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Lupus Coagulation Inhibitor / analysis
Takayasu Arteritis / immunology*,  pathology
Vasculitis / immunology,  pathology
Chemical
Reg. No./Substance:
0/Antibodies, Antiphospholipid; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Lupus Coagulation Inhibitor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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