| Takayasu disease presenting as malignant pyoderma gangrenosum in a child with relapsing polychondritis. | |
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MedLine Citation:
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PMID: 19119133 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 7-year-old Lebanese girl with recently diagnosed relapsing polychondritis had a 1-month history of several painful ulcerations involving her entire body. Skin biopsy was consistent with the diagnosis of pyoderma gangrenosum. She was hospitalized and started on intravenous steroids with partial improvement. During her hospital stay, she developed right wrist drop. Radiologic studies revealed a large aortic aneurysm and an axillary aneurysm compressing the right brachial nerve plexus. Pathology of the resected aortic anyeurism confirmed the diagnosis of Takayasu's arteritis. The patient was started on infliximab therapy with complete resolution of her skin lesions and improvement in hand function. |
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Authors:
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Samer Ghosn; Joelle Malek; Zuhair Shbaklo; Mona Matta; Imad Uthman |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 59 ISSN: 1097-6787 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2009-01-02 Completed Date: 2009-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: S84-7 Citation Subset: IM |
Affiliation:
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Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon. sg03@aub.edu.lb |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal
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therapeutic use Aortic Aneurysm, Thoracic / etiology, pathology, radiography Child Female Humans Polychondritis, Relapsing / complications*, diagnosis, drug therapy Pyoderma Gangrenosum / diagnosis, drug therapy, etiology* Takayasu Arteritis / diagnosis, drug therapy, etiology*, pathology Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/infliximab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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