Document Detail

Takayasu arteritis presenting as retinal and vertebrobasilar ischemia.
MedLine Citation:
PMID:  2570149     Owner:  NLM     Status:  MEDLINE    
A young woman presented with a 4-month history of retinal and vertebrobasilar ischemia. Angiography demonstrated narrowing of major branches of the aortic arch. Intractable, severe retroorbital pain of the right eye developed after a middle cerebral artery stroke. During 4 weeks of aggressive immunosuppressive therapy including IV high dose bolus corticosteroids and pulse cyclophosphamide, her neurologic deficit improved transiently, but her retroorbital pain persisted. She died of staphylococcal sepsis and pneumonia. An autopsy demonstrated thrombotic or fibrous occlusion, with minimal inflammation, of extracranial arteries.
K K Edwards; H B Lindsley; C W Lai; P J Van Veldhuizen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  16     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-09-29     Completed Date:  1989-09-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1000-2     Citation Subset:  IM    
Department of Medicine, University of Kansas Medical Center, Kansas City 66103.
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MeSH Terms
Aortic Arch Syndromes / diagnosis*
Cerebrovascular Disorders / complications,  physiopathology
Diagnosis, Differential
Immunosuppressive Agents / therapeutic use
Ischemia / diagnosis*
Orbit / physiopathology
Retinal Vessels*
Takayasu Arteritis / diagnosis*,  drug therapy
Vertebrobasilar Insufficiency / diagnosis*
Reg. No./Substance:
0/Immunosuppressive Agents

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