Document Detail

Tailoring silver nanodots for intracellular staining.
MedLine Citation:
PMID:  21063587     Owner:  NLM     Status:  MEDLINE    
Through tailored oligonucleotide scaffolds, Ag nanocluster syntheses have yielded thermally and cell-culture medium stable silver cluster-based emitters. Optimizing ssDNA stability has enabled creation of highly concentrated and spectrally pure nanocluster emitters with strong intracellular emission. Both fixed and live-cell staining become possible, and intracellular delivery is demonstrated both through conjugation to cell-penetrating peptides and via microinjection.
Sungmoon Choi; Junhua Yu; Sandeep A Patel; Yih-Ling Tzeng; Robert M Dickson
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-11-09
Journal Detail:
Title:  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology     Volume:  10     ISSN:  1474-9092     ISO Abbreviation:  Photochem. Photobiol. Sci.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  2011-04-18     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  101124451     Medline TA:  Photochem Photobiol Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  109-15     Citation Subset:  IM    
School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA.
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MeSH Terms
Cell-Penetrating Peptides / chemistry*
DNA, Single-Stranded / chemistry
Metal Nanoparticles / chemistry*,  radiation effects
Microscopy, Confocal
NIH 3T3 Cells
Silver / chemistry*
Spectrophotometry, Ultraviolet
Staining and Labeling
Grant Support
R01 GM086195-03/GM/NIGMS NIH HHS; R01 GM086195-04/GM/NIGMS NIH HHS; R01-AI061031/AI/NIAID NIH HHS; R01-GM086195/GM/NIGMS NIH HHS
Reg. No./Substance:
0/Cell-Penetrating Peptides; 0/DNA, Single-Stranded; 7440-22-4/Silver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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