| Tailoring silver nanodots for intracellular staining. | |
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MedLine Citation:
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PMID: 21063587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Through tailored oligonucleotide scaffolds, Ag nanocluster syntheses have yielded thermally and cell-culture medium stable silver cluster-based emitters. Optimizing ssDNA stability has enabled creation of highly concentrated and spectrally pure nanocluster emitters with strong intracellular emission. Both fixed and live-cell staining become possible, and intracellular delivery is demonstrated both through conjugation to cell-penetrating peptides and via microinjection. |
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Authors:
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Sungmoon Choi; Junhua Yu; Sandeep A Patel; Yih-Ling Tzeng; Robert M Dickson |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-11-09 |
Journal Detail:
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Title: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Volume: 10 ISSN: 1474-9092 ISO Abbreviation: Photochem. Photobiol. Sci. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-24 Completed Date: 2011-04-18 Revised Date: 2012-01-04 |
Medline Journal Info:
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Nlm Unique ID: 101124451 Medline TA: Photochem Photobiol Sci Country: England |
Other Details:
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Languages: eng Pagination: 109-15 Citation Subset: IM |
Affiliation:
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School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell-Penetrating Peptides / chemistry* DNA, Single-Stranded / chemistry Metal Nanoparticles / chemistry*, radiation effects Mice Microscopy, Confocal NIH 3T3 Cells Silver / chemistry* Spectrophotometry, Ultraviolet Staining and Labeling |
| Grant Support | |
ID/Acronym/Agency:
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R01 GM086195-03/GM/NIGMS NIH HHS; R01 GM086195-04/GM/NIGMS NIH HHS; R01-AI061031/AI/NIAID NIH HHS; R01-GM086195/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Cell-Penetrating Peptides; 0/DNA, Single-Stranded; 7440-22-4/Silver |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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