Document Detail


Tailored treatment for HIV+ persons with mental illness: the intervention cascade.
MedLine Citation:
PMID:  23673886     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The public health literature demonstrates disturbingly high HIV risk for persons with a serious mental illness, who are concurrently comorbid for substance abuse. Many HIV positives have not been tested and therefore do not know their status, but for individuals who are triply diagnosed, adherence to HIV treatment results in meaningful reductions in viral loads and CD4 counts. Barriers to treatment compliance are reviewed, low-threshold/low-intensity community-based interventions are discussed, and preliminary evidence is presented for the efficacy of the intervention cascade, defined as an integrated intervention delivered by specially trained nurses who individualize a treatment compliance intervention in real time as an adaptive response to demand characteristics of the individual.
Authors:
Michael B Blank; Marlene M Eisenberg
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  63 Suppl 1     ISSN:  1944-7884     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-15     Completed Date:  2013-07-19     Revised Date:  2014-06-18    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S44-8     Citation Subset:  IM; X    
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MeSH Terms
Descriptor/Qualifier:
Behavior Therapy / methods*
CD4 Lymphocyte Count
Community Health Services*
Comorbidity
HIV Infections / complications,  therapy*
Health Promotion / organization & administration*
Humans
Mental Disorders / complications,  therapy*
Patient Compliance
Risk Factors
Substance-Related Disorders / complications,  therapy*
Treatment Outcome
Viral Load
Grant Support
ID/Acronym/Agency:
#R01NR008851/NR/NINR NIH HHS; P30 AI 045008/AI/NIAID NIH HHS; P30 AI045008/AI/NIAID NIH HHS; P30 MH097488/MH/NIMH NIH HHS; R01 NR008851/NR/NINR NIH HHS; R13 HD074468/HD/NICHD NIH HHS; R13 MH081733/MH/NIMH NIH HHS; R13MH-081733-01A1/MH/NIMH NIH HHS
Comments/Corrections

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