| Tadalafil in the management of severe pulmonary artery hypertension. | |
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MedLine Citation:
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PMID: 18984932 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Severe oyknibart arterial hypertension is a life-threatening disease with a poor prognosis. Continuous intravenous infusion of prostacyclin has proved effective in this condition. However, it carries the risk of serious complications arising from the complex delivery system along with a high cost. Prostacyclin analogs, endothelin antagonists, and the phophodiesterase-5 inhibitor sildenafil are emerging and promisinge therapies. Tadalafil, like sildenafil, is a selective phosphodiesterase-5 inhibitor with a longer duration of action. We repport the use of tadalafil in two patients of severe pulmonary arterial hypertension who could not afford expensive treatment. |
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Authors:
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Thokchom Sd Singh; Dilip Kumar; Soumik Basu; Manotosh Panja; Bishwanath Mitra |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian heart journal Volume: 58 ISSN: 0019-4832 ISO Abbreviation: Indian Heart J Publication Date: 2006 Jan-Feb |
Date Detail:
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Created Date: 2008-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374675 Medline TA: Indian Heart J Country: India |
Other Details:
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Languages: eng Pagination: 52-3 Citation Subset: IM |
Affiliation:
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Department of Medicine and Cardiology, Regional Institute of Medical Sciences, Imphal. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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