Document Detail


Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness.
MedLine Citation:
PMID:  22943271     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report an open-label study comparing tadalafil and acetazolamide (n = 24) versus acetazolamide (n = 27) for prevention of high-altitude illness (HAI) at Mt. Kilimanjaro. Tadalafil group had lower rates of severe HAI compared with controls (4% vs 26%, p = 0.03), mostly because of decreased high-altitude pulmonary edema rates (4% vs 22%, p = 0.06).
Authors:
Eyal Leshem; Yehezkel Caine; Elliot Rosenberg; Yoram Maaravi; Hagai Hermesh; Eli Schwartz
Publication Detail:
Type:  Journal Article     Date:  2012-07-30
Journal Detail:
Title:  Journal of travel medicine     Volume:  19     ISSN:  1708-8305     ISO Abbreviation:  J Travel Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9434456     Medline TA:  J Travel Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  308-10     Citation Subset:  IM    
Copyright Information:
© 2012 International Society of Travel Medicine.
Affiliation:
Center for Geographic Medicine and Internal Medicine C, Sheba Medical Center, Tel-Hashomer and Sackler Faculty of Medicine, Tel Aviv, Israel.
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