Document Detail


Tacrolimus as basic immunosuppression in pregnancy after renal transplantation. A single-center experience.
MedLine Citation:
PMID:  16386528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Renal transplantation restores fertility within an average of 6 months, so women of childbearing age are able to consider pregnancy. Successful pregnancies have been reported in recent years under different immunosuppressive regimens, but the optimal treatment to achieve the maximum safety for both the mother and fetus remains unclear. Tacrolimus has been demonstrated to provide long-term immunosuppression and prevent rejection in most renal transplants. It seems safe, but experience is limited compared with cyclosporine. We report our experience highlighting the high rate of successful pregnancies attained in women treated with tacrolimus as the basic immunosuppressant and advised of recommendations to achieve a healthy newborn. Renal function was preserved during the pregnancy. The puerperal period and the rate of gestation-related difficulties appeared similar to that of the general population.
Authors:
J A Garcia-Donaire; M Acevedo; M J Gutiérrez; M J Manzanera; E Oliva; E Gutiérrez; A Andrés; J M Morales
Related Documents :
22384428 - Laparoscopic management of early primary peritoneal pregnancy: a case report.
16167758 - Midline lethal granuloma complicating pregnancy: case report.
18837808 - Practical assessment of maternal cardiovascular risk in pregnancy.
6313918 - Pregnancy complicated by herpes zoster. a report of two cases and literature review.
21082538 - Maternal periodontal disease is associated with oxidative stress during pregnancy.
19951008 - Heparin for patients with growth restricted fetus: a prospective randomized controlled ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  37     ISSN:  0041-1345     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-01-02     Completed Date:  2006-02-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3754-5     Citation Subset:  IM    
Affiliation:
Renal Transplant Unit, Hospital 12 de Octubre, Madrid, Spain. docdonaire@terra.es
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Female
Humans
Immunosuppressive Agents / therapeutic use*
Kidney Transplantation / immunology*
Pregnancy
Pregnancy Complications / immunology*
Pregnancy Outcome
Retrospective Studies
Tacrolimus / therapeutic use*
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 109581-93-3/Tacrolimus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interaction between omeprazole and tacrolimus in renal allograft recipients: a clinical-analytical s...
Next Document:  Comparison of quantitative PCR and antigenemia in cytomegalovirus infection in renal transplant reci...