| Tachycardias of right ventricular origin. | |
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MedLine Citation:
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PMID: 1739956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ventricular tachycardia arising from the right ventricle usually has a left bundle branch morphology and occurs in a variety of disorders. Uhl's anomaly and right ventricular dysplasia may represent a spectrum of one disorder and are a cause of right heart dilatation, failure, and premature sudden death due to ventricular arrhythmias. Familial forms of the disorder may account for focal clustering in some geographic areas. Management should involve aggressive stratification of arrhythmia risk and may include medical, surgical, or device therapy. In contrast, the syndrome of right ventricular outflow tract tachycardia, including nonischemic exercise-induced and repetitive monomorphic ventricular tachycardia, is a more benign entity. Management often involves beta- and calcium channel blocking drugs or type IC antiarrhythmic drugs. Catheter ablation of the arrhythmia focus in the right ventricular outflow tract has been used in selected patients. In this syndrome the right ventricle is normal, and noninvasive testing as well as electrophysiologic studies can be helpful in distinguishing it from the more malignant right ventricular dysplasia. Ventricular arrhythmias may also be seen after right ventricular incision, as in surgical repair of tetralogy of Fallot and ventricular septal defects. Significant ventricular ectopy associated with an abnormal right ventricle (enlarged or depressed systolic function) is associated with an increased risk for sustained arrhythmia and sudden cardiac death in this group. The optimal indicator(s) of highest risk in these patients remains under investigation but will likely include electrophysiologic testing. Bifascicular block occurs commonly after repair of tetralogy of Fallot, but is usually benign. Isolated right ventricular infarction is rare. Most right ventricular arrhythmias associated with ischemia occur in the setting of iatrogenic catheter manipulation for pacing or hemodynamic monitoring. In conclusion, right ventricular arrhythmias involve an unusual and interesting group of clinical entities and appear to span the spectrum of arrhythmias mechanisms. A macroreentrant activation ring around the ventriculotomy scar may account for the arrhythmias following repair of tetralogy of Fallot. Microreentry at sites of morphologic abnormalities results in the arrhythmias associated with right ventricular dysplasia and ischemia. Triggered activity related to DADs or, less likely, abnormal automaticity, produce repetitive monomorphic ventricular tachycardia and nonischemic exercise-induced ventricular tachycardia, both of which usually originate from the right ventricular outflow tract. Iatrogenic ventricular tachycardia associated with catheter manipulation is especially likely to occur in the presence of right ventricular ischemia and infarction. It is important to recognize these clinical entities because treatment is specific.(ABSTRACT TRUNCATED AT 400 WORDS) |
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Authors:
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D H Hoch; L E Rosenfeld |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cardiology clinics Volume: 10 ISSN: 0733-8651 ISO Abbreviation: Cardiol Clin Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-03-20 Completed Date: 1992-03-20 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8300331 Medline TA: Cardiol Clin Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 151-64 Citation Subset: IM |
Affiliation:
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Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bundle of His
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physiopathology Coronary Disease / complications Electrocardiography Heart Defects, Congenital / surgery Humans Postoperative Complications / etiology Tachycardia* / etiology, physiopathology Ventricular Function, Right / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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