Document Detail


Tachycardia-related cardiomyopathy: a common cause of ventricular dysfunction in patients with atrial fibrillation referred for atrioventricular ablation.
MedLine Citation:
PMID:  10943231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the frequency of tachycardia-related cardiomyopathy in patients with atrial fibrillation and systolic dysfunction referred for atrioventricular node ablation.
PATIENTS AND METHODS: This prospective multicenter cohort study was conducted at 16 tertiary care centers. The ejection fraction was measured before and 3 and 12 months after atrioventricular node ablation. Patients with reduced systolic function (ejection fraction < or = 45%) before atrioventricular ablation were included in this study. Patients whose ejection fraction increased by at least 15 percentage points and to higher than 45% were considered to have tachycardia-related cardiomyopathy.
RESULTS: Of 63 patients with systolic dysfunction, 48 had at least 1 adequate follow-up echocardiographic study. Sixteen (25%) of the 63 had marked improvement in the ejection fraction (mean +/- SD change, 27 +/- 8 percentage points) to a value higher than 45% after ablation.
CONCLUSIONS: Tachycardia-related cardiomyopathy is common in patients with atrial fibrillation and systolic dysfunction referred for atrioventricular node ablation. This diagnosis should be considered in all patients in whom systolic dysfunction occurs subsequent to or concomitant with onset of atrial fibrillation.
Authors:
M M Redfield; G N Kay; L S Jenkins; M Mianulli; D N Jensen; K A Ellenbogen
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  75     ISSN:  0025-6196     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-07     Completed Date:  2000-09-07     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  790-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / complications*,  physiopathology,  therapy,  ultrasonography
Atrioventricular Node
Cardiomyopathies / complications*,  etiology*,  physiopathology,  ultrasonography
Catheter Ablation
Humans
Prospective Studies
Registries
Stroke Volume
Systole
Time Factors
Treatment Outcome
Ventricular Dysfunction, Left / etiology*,  physiopathology,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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