| Tachycardia during reversal of one-kidney, one-clip hypertension in conscious rats. | |
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MedLine Citation:
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PMID: 2006999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The efferent sympathetic activity of the heart was investigated during reversal of one-kidney, one-clip (1K,1C) hypertension in conscious, freely moving rats using changes in heart rate as an index. One-kidney, one-clip hypertensive rats presented marked tachycardia during the first 8 h after unclipping. Mean arterial pressure fell 28% 3 h after unclipping and 37% 8 h after unclipping. In a separate experiment, short term infusion (15 min) of sodium nitroprusside in conscious freely moving rats produced similar tachycardia in hypertensive and sham-operated rats. The present results indicate that the baroreceptor reflex of the heart was operating normally during the prompt reversal of hypertension after unclipping. |
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Authors:
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B H Machado; H C Salgado |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of hypertension Volume: 4 ISSN: 0895-7061 ISO Abbreviation: Am. J. Hypertens. Publication Date: 1991 Jan |
Date Detail:
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Created Date: 1991-04-30 Completed Date: 1991-04-30 Revised Date: 2009-02-24 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 60-3 Citation Subset: IM |
Affiliation:
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Department of Physiology, School of Medicine of Ribeirão Preto, USP, São Paulo, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure Heart Rate Hypertension, Renal / physiopathology* Male Nephrectomy Pressoreceptors / physiology Rats Rats, Inbred Strains Reflex / physiology Tachycardia / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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