Document Detail

TachoSil for postinfarction ventricular free wall rupture.
MedLine Citation:
PMID:  22419793     Owner:  NLM     Status:  MEDLINE    
Despite a decline in the last three decades, postinfarction ventricular free wall rupture still complicates more than 3% of acute ST-elevation myocardial infarctions and remains a surgical challenge. TachoSil (Nycomed, Zurich, Switzerland) is an equine collagen patch coated with human fibrinogen and human thrombin, which has recently been used for haemostasis in cardiovascular surgery, but its potential usefulness in free wall rupture has not been reported. Initial clinical experience with an on-pump sutureless technique without cardioplegia, using wide TachoSil patching to achieve free wall rupture repair, has been described.
Marco Pocar; Davide Passolunghi; Alda Bregasi; Francesco Donatelli
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Publication Detail:
Type:  Journal Article     Date:  2012-03-14
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  14     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-16     Completed Date:  2012-09-07     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  866-7     Citation Subset:  IM    
Department of Cardiovascular Sciences, Università degli Studi di Milano, Scientific Institute MultiMedica Hospital, Milan, Italy.
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MeSH Terms
Cardiac Surgical Procedures*
Cardiac Tamponade / etiology,  surgery
Cardiopulmonary Bypass
Drug Combinations
Fibrinogen / therapeutic use*
Heart Rupture, Post-Infarction / etiology,  surgery*
Hemostatic Techniques*
Hemostatics / therapeutic use*
Thrombin / therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Drug Combinations; 0/Hemostatics; 0/TachoSil; 9001-32-5/Fibrinogen; EC
Comment In:
Interact Cardiovasc Thorac Surg. 2012 Jun;14(6):868   [PMID:  22589352 ]

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