Document Detail


"TORCing" neutrophil chemotaxis.
MedLine Citation:
PMID:  21145496     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils.
Authors:
Pascale G Charest; Richard A Firtel
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Developmental cell     Volume:  19     ISSN:  1878-1551     ISO Abbreviation:  Dev. Cell     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-01-24     Revised Date:  2014-09-16    
Medline Journal Info:
Nlm Unique ID:  101120028     Medline TA:  Dev Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  795-6     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 GM037830/GM/NIGMS NIH HHS; R01 GM037830-23/GM/NIGMS NIH HHS
Comments/Corrections
Comment On:
Dev Cell. 2010 Dec 14;19(6):845-57   [PMID:  21145500 ]

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